Biomedical Research

Purpose: To discuss on the correlation between the blood stasis syndrome of coronary heart disease and coagulation function and blood platelet parameters.

Method: 74 cases of coronary heart disease patients are selected as the objectives of the research, including 50 patients with syndrome of blood stasis and 24 patients without syndrome of blood stasis. The Prothrombin Time (PT), the Activated Partial Thromboplastin Time (APTT), the Fibrinogen (FIB), the blood Platelet count (PLT), the Platelet Distribution Width (PDW), the Mean Platelet Volume (MPV), the large platelet ratio (PLCR) and the Thrombocytocrit (PCT) of patients of the two groups are inspected, and International Normalized Ratio (INR) is calculated, and the levels of various indexes are compared between the two groups. In addition, the Pearson correlation test is adopted to analyse the correlation between the blood stasis syndrome of coronary heart disease and various indexes. The binary logistic regression analysis is adopted to discuss on the influencing factors for the blood stasis syndrome of the coronary heart disease.

Results: The PT and INR of the group with the blood stasis syndrome are significantly lower than those of the group without the blood stasis syndrome (P<0.05). The difference on various indexes related to blood platelet has no statistical significance (P>0.05). There is correlation between the blood stasis syndrome of coronary heart disease and PT and INR (P<0.05). INR is the influencing factor on the blood stasis syndrome of coronary heart disease.

Conclusion: There is a close correlation between the blood stasis syndrome of coronary heart disease and the coagulation function: INR reduces when PT shortens.

Author(s): Jun Gong, Ning Gu
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