Biomedical Research

Cardiovascular Autonomic Neuropathy (CAN) is one of the most overlooked complications of DM and is clinically important because of its life threatening consequences. CAN results from damage to the autonomic nerve fibers that innervate the heart and blood vessels and it causes abnormalities in control of heart rate and vascular dynamics .The present study was designed to assess the cardiovascular autonomic function in type 2 DM. The cardiovascular autonomic function have been conducted in 30 cases of type II DM and 30 controls, aged between 30-50 years, Including both genders, by using Deep breathing test (DBT), Valsalva Maneuvre (VM), Cold Pressor Test (CPT), Lying to standing test (LST) and its correlation with duration of diabetes. The duration of DM was negatively correlated with delta heart rate (-0.908), valsalva ratio (-0.926), rise in diastolic pressure during hand grip test (– 0.747) and cold pressor test (-0.888). From this study it is concluded that, the duration of diabetes has more effect of CAN.

Author(s): Bandi Hari Krishna, Mallikarjuna Reddy N, Sharan B, Singh M, Sasi Kala P, Kiran Kumar C H, Uma B V, Vijetha P, Shravya Keerthi G
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