Biomedical Research

Purpose: To discuss on the difference of Mycoplasma pneumoniae pneumonia (MPP) combined cardiac damage on gender and age as well as the clinical significance.

Method: 210 child patients of mycoplasma pneumoniae pneumonia received and cured in the Department of Urology, the First Affiliated Hospital of Zhengzhou University during January 2013- August 2014 are taken as the research objectives. The serum Lactate Dehydrogenase (LDH), Creatine Kinase (CK) and Creatine Kinase MB (CK-MB) levels of the child patients are detected on the second day they are admitted to the hospital and the correlations on age and gender are analysed.

Results: Among the 210 MPP patients, there are 123 boys and 87 girls, with the proportion of 1: 1.41. The myocardial enzyme levels of MPP child patients are increased by various extents, in which the CK (249.14) and CK-MB (44.71) of girls are significantly higher than that of boys (219.85 and 32.87) (P<0.05); however, there is no difference on the serum LDH level between boys and girls. On the aspect of ages, the serum myocardial enzyme of all age groups increases. In which the serum CK and CK-MB levels increase more insignificantly in younger patients than that of older ones (P<0.05). With the increase in ages, the rise on CK and CK-MB levels declines, with a negative correlation with ages. However, there is no significant difference on serum LDH levels of various age groups (P>0.05).

Conclusion: The child patients of mycoplasma pneumoniae pneumonia suffer from cardiac damage to different extents in which girl patients and infant patients of mycoplasma pneumoniae pneumonia have severer extent on cardiac damage. The serum myocardial enzyme spectrum detection can be utilized to detect the cardiac damage in time, and intervention measures shall be adopted.

Author(s): Tao Wang, Yafei Ding, Yan Shi, Zhenlin Huang, Yinghui Ding, Zhankui Jia, Jinjian Yang
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