Biomedical Research

Objective: To explore the characteristics of cerebral vascular angiography from transient ischemic attack (TIA) accompanied with type 2 diabetes (T2D).

Methods: TIA patients with complete data in Tianjin Teda Hospital were retrospectively analyzed from December 2011 to November 2015 and 336 patients were taken up, which were divided into T2D group (152 cases) and control group (184 cases). By use of C type arm angiography system, cerebral vascular stenotic degrees, determination of intracranial or extracranial artery, and the collateral compensative capacity were compared between two groups.

Results: Cerebral vessel stenotic degree was significantly different between T2D group and the control group (χ²=20.03, P<0.05). Patients with moderate to severe stenosis and occlusion were more in T2D group than those in the control group (χ²=18.94, P<0.05). Control group was mainly with non-diffuse vascular lesions and compensatory form collateral vessels. In 3 subgroup, with the increase of glycosylated hemoglobin (unsatisfactory blood glucose control), the incidence rate of moderate and severe stenosis was increasing significantly (P<0.05).

Conclusion: Severe cerebral vascular stenosis is more easy to happen in patients of TIA accomplicated with T2D, which was distinguished by multiple vascular lesions, diffuse vascular lesions and less collateral compensative capacity. Unsatisfactory blood glucose control was a bad factor for these patients.

Author(s): Dayong Du, Yanchao Shi, Hang Xu, Heliang Zhang, Zaiyu Guo
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