Biomedical Research

Purpose: This research was aimed to explore the clinical situations of solifenacin succinate combined with tamsulosin in treating OAB after TURP.

Methods: During experiment, the diagnosed subjects were randomly included into the treatment group and control group, the treatment lasted 7~10 d, 5 mg of solifenacin succinate and 0.2 mg of tamsulosin were given by oral administration once every one day. Scores were assessed as per relevant reference standards (OABSS, IPSS and QOP) before and after treatment.

Results: In treatment group, compared with before treatment group, OABSS, IPSS and QOP after treatment decreased significantly after treatment (p<0.05). In control group, compared with before control group, OABSS, IPSS and QOP after treatment decreased significantly after treatment (p<0.05).

Conclusion: It can be seen that the solifenacin succinate combined with other drugs has obvious curative effects and less side effects, which can benefit patients in the quality of life and disease treatment.

Author(s): Jiasheng Hu, Dongxu Zhang, Jun Guan
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