Biomedical Research

Objective: To evaluate the auxiliary efficacy and safety of Nasaleze nasal spray applied to Chinese population with allergic rhinitis.

Methods: 120 patients were selected who were diagnosed with allergic rhinitis, and were randomly divided into two groups: experimental group and control group (the patients in experimental group use Mometasone Furoate Aqueous nasal spray for one spray and Nasaleze nasal spray in the morning and only Nasaleze nasal spray in the evening; the patients in control group respectively Mometasone Furoate Aqueous nasal spray for one spray. The research circle for the two groups is both 2 weeks), and respectively compare the changes in symptoms and sign score of the two groups before and after treatment and the differences between the two groups.

Results: Symptom score and sign score of the two groups are both obviously improved after treatment (P<0.001); the efficacy of experimental group and control group is respectively 86.66% and 90.00%. And there is no obviously difference between the two groups (P>0.05); there is no obviously adverse reactions between the two groups.

Conclusion: When hormonal nasal spray and Nasaleze nasal spray are combined, the efficacy is equivalent to the single hormone. When hormonal nasal spray and Nasaleze nasal spray were simultaneously applied to the patients with allergic rhinitis, they can effectively reduce the use of nasal spray hormone and be with good safety.

Author(s): Haiyun Shi, Yan Zhuang, Xueyan Wang
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