Biomedical Research

Objective: To investigate the clinical efficacy of noninvasive positive pressure ventilation in the treatment of elderly patients with severe pneumonia and respiratory failure.

Methods: A total of 85 elderly patients with severe pneumonia and respiratory failure treated in our hospital from November 2016 to June 2017 were divided according to different treatment methods as control group including 35 cases treated by routine treatment and experimental group including 50 cases treated by noninvasive positive pressure ventilation, the curative effect and resulting influence were compared between the two groups.

Results: Before treatment, no significant difference was found between the two groups in blood gas indexes of PaO₂ and PaCO₂ (P>0.05); while after treatment, the level of PaO₂ was significantly higher (P<0.05) and the level of PaCO₂ significantly lower in the experimental group compared with the control group (P<0.05). Before treatment, there was no significant difference between the two groups in indexes of HR, RR and SaO₂ (P>0.05); while after treatment, the indexes of HR as well as RR were significantly lower (P<0.05) and the SaO₂ index was significantly higher in the experimental group compared with the control group (P<0.05), the positive pressure ventilation time and hospitalization time of the experimental group were significantly shorter than those of the control group of statistical significance, (P<0.05).

Conclusion: In treatment of elderly patients with severe pneumonia and respiratory failure, noninvasive positive pressure ventilation is effective in improving blood gas indexes, ECG monitoring signs and clinical indicators in patients, thus worthy of clinical popularization and application.

Author(s): Ruilai Jiang, Ying Hua, Shuiyun Meng, Yanbin Wei, Xiaocheng Huang
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