Biomedical Research

Objective: This research aims to find out the clinical curative effect and safety of Lianhuaqingwen capsule against epidemic respiratory infection.

Methods: The observation objects include 2000 patients with epidemic infection of the upper respiratory tract who came to our hospital from June 2012 to June 2015. Using the random number table method, I divide the patients into two groups: the experimental group and the control group, each group including 1000 patients. During the treatment, patients in both groups are treated in the conventional way. What makes the difference is that Lianhuaqingwen capsules are administered to patients in the experimental group three times a day (four capsules each time) orally additionally; then, on the third, the seventh and the tenth day of the treatment, the clinical results of the two groups of patients with the epidemic infection of the upper respiratory tract are analyzed.

Results: According to the results of contrast test, it can be known that the time of fever relieving (3.01 ± 0.82 d), cough disappearing (3.14 ± 1.02 d) and chest X-ray shadow vanishing (4.52 ± 1.14 d), and the clinical course (6.31 ± 1.04 d) of patients in the experimental group are significantly shorter than time of fever relieving (4.52 ± 1.32 d), cough disappearing (4.90 ± 1.40 d) and chest X-ray shadow vanishing (5.91 ± 1.48 d), and the clinical course (8.92 ± 1.64 d) in the control group (P<0.05). The difference between the two group is of statistical value. The clinical curative effective rate if experimental group is (92.00%), which is significantly higher than that (78.00%) of control group (P<0.05), and the intergroup difference is of statistical significance.

Conclusion: Using Lianhuaqingwen capsules in the clinical treatment of epidemic infection of upper respiratory tract is effective and reliable. Being able to alleviate clinical symptoms like fever and cough effectively, and having such a great clinical value in lung infection control, the medicine is worth being promoted and used in clinical practice.

Author(s): Haizhu Zhang, Zufang Li, Mengchen Sha, Daoxun Wu
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