Biomedical Research

Objective: This study aims to observe the clinical effects of levamlodipine and amlodipine in mild and moderate hypertension.

Methods: A total of 110 patients diagnosed with mild and moderate hypertension in our hospital from April 2015 to February 2017 were selected and randomly divided into control group and observation group by the odd-even method. The control group (55 cases) was treated with amlodipine in clinics, whereas the observation group (55 cases) was treated with levamlodipine. Finally, the evaluation results of blood pressure indexes, disease effect, treatment satisfaction, and blood index of the two groups were compared.

Results: The blood pressure indexes of the observation group significantly improved compared with that of the control group (P<0.05). The therapeutic effect of the observation group is 98.18%, which is considerably higher than that of the control group (76.36%) (P<0.05). The treatment satisfaction of the observation group is 98.18% while that of the control group is 72.73% (P<0.05). The blood indexes of the observation group improved significantly compared with that of the control group (P<0.05).

Conclusions: Levamlodipine is superior to amlodipine in terms of the improvement of blood pressure indexes, disease effect, treatment satisfaction, and blood indexes in patients with mild and moderate hypertension. Thus, levamlodipine optimizes prognosis of patients with mild and moderate hypertension.

Author(s): Chang Hui, Ying-Qiang Guo, Zhi-Cai Yang, Xiao-Kang Ning, Li-Ming Yue
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