Biomedical Research

Objective: To compare the effect of the anterior versus posterior surgical approach combined with debridement, bone grafting and instrumentations for the patients with multi-segments spinal tuberculosis.

Methods: 98 patients with multi-segments spinal tuberculosis in our hospital from September 2015 to October 2017 were collected into this study, including 50 patients in the control group with the anterior surgery and 48 patients in the observed group with the posterior operation. The results of clinical efficacy, the bleeding volume, the operation time, the hospital stay, the incidence of complications, the serum values of erythrocyte sedimentation rate (ESR),C reactive protein (CRP) and Cobb’s angle were compared between the control group and observed group.

Results: The total efficacy rate of patients in the control and observed group were respectively 92.0% and 95.836% (P>0.05). After the surgery, the hospital stay and the incidence of complications in the observed group were less than the control group (P<0.05). The serum values of ESR, CRP and Cobb’s angle after surgery in both groups were lower than before treatment (P<0.05), and the serum values of ESR, CRP and Cobb’s angle after surgery in the observed groups were lower than the control group (P<0.05).

Conclusion: It’s suggested that posterior surgical approach decrease the complications, improve the clinical symptoms and kyphosis of patients with multi-segments spinal tuberculosis, which is worthy to be clinically popularized.

Author(s): Zhuang Huirong, Feng Chao, Gao Di
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