Biomedical Research

Objective: To investigate clinical significance of Amomum villosum Lour extract for the treatment of functional dyspepsia resulting from deficiency of spleen and stomach. Methods: From February 11, 2016 to January 5, 2017, 88 cases of functional dyspepsia in our hospital were selected as the objects and randomly divided into two groups (control group and observation group). The control group took mosapride treatment while the observation group was treated with extract of Amomum villosum Lour. The clinical effects, TCM symptoms, quality of life and adverse events of the two groups were observed. Results: In the observation group, the total effective rate (95.45%) was significantly higher compared with that of the control group (77.27%) of statistical significance, P<0.05; the TCM syndrome scores 9.65 ± 1.08 and the score of life quality 86.89 ± 2.47 after treatment were better than those of the control group, P<0.05; and there was no significant difference in adverse events between the two groups with no serious consequences, P>0.05. Conclusion: the extract of Amomum villosum Lour can be used to treat functional dyspepsia caused by deficiency of spleen and stomach with definite effects of security and it can effectively alleviate the suffering of patients, help disease control and improve the quality of life.

Author(s): Zhenbo Wang, Fang Chen, Weiwei Jiang
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