Biomedical Research

Aim: To investigate the effect of continuous blood purification in the treatment of septic shock from renal dysfunction.

Methods: From January 2015 to August 2016, a total of 71 patients suffering septic shock from renal dysfunction were selected as the objects. All patients were randomly divided into control group (36 cases) and experimental group (35 cases). Patients in control group were treated with hemodialysis and those in experiment group were treated with continuous blood purification. The efficacy of those two treatments were analysed and compared.

Results: In the experimental group, there was significant difference in indicators of PH, HCO₃ and PaO₂ after treatment compared with pre-treatment ones, P<0.01. While, in the control group, there was significant difference only in indicators of pH and HCO₃ after treatment compared with the values before treatment, P<0.01. After treatment, the concentration of PH, HCO₃ and PaO₂ was 7.34 ± 0.02 mM, 23.9 ± 2.9 mM and 90.5 ± 7.5 mM in the experimental group and 7.25 ± 0.03 mM, 17.1 ± 2.6 mM and 66.2 ± 7.2 mM in the control group. Total effective rate was 85.71% (30/35) in the experimental group and 63.89% (23/36) in the control group.

Conclusion: Compared with conventional hemodialysis, continuous blood purification is better, thus worth being spread and applied in clinic.

Author(s): Fang Tong, Song Li, Na Yang
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