Biomedical Research

Objective: To analyse combinational effect of pulsed dye laser and propranolol on treatment of Superficial Hemangioma (SH).

Methods: From June 2016 to June 2017, we collected 110 children with SH enrolled in Linyi No.3 People's Hospital. All patients were divided randomly and evenly into two groups (control group and study group). The patients in control group were treated with pulsed dye laser, while patient in study group were treated with pulsed dye laser and propranolol. The efficacies of those two different treatment methods were analysed and compared.

Results: The heart rate of the control group is 143.29 ± 5.96 times/min, but that of the study group is 120.03 ± 2.36 times/min. Moreover, the efficacy rate in the study group was 98.18% (54/55), which is higher than 74.55% (41/55) in the control group. Meanwhile, the adverse reaction rate in the study group is 3.64% (2/55), which is lower than 20.00% (11/55) in the control group.

Conclusion: Combination of pulsed dye laser and propranolol is effective in the treatment of superficial hemangioma.

Author(s): Xuejian Liu, Wenchuan Yang, Maozhong Tai, Yuhua Li, Xia Wu, Xiangli Chen
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