Biomedical Research

Objective: To compare the clinical efficacy between epidural anesthesia and lumbar combined with epidural anesthesia applied during caesarean section.

Methods: A total of 120 pregnant women undergoing caesarean section in the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University between Jan 2014 and Jan 2016 were recruited in this clinical trial. All participants were randomly divided into the control and observation groups (n=60). In the control group, epidural anesthesia was administered during caesarean section and lumbar combined with epidural anesthesia was implemented in the observation group. The quality of anesthesia, onset time of anesthesia, time of motor blockage recovery time and anesthesia-induced adverse reactions were statistically compared between two groups.

Results: In the observation group, the excellent rate of anesthesia was calculated as 98.33%, significantly higher compared with 85.00% in the control group (χ2=6.521, P<0.05). In the observation group, the onset time of anesthesia (t=26.212, P=0.001) and time of motor blockage recovery were significantly shorter compared with those in the control group (t=12.582, P<0.001). The incidence rate of adverse reactions induced by anesthesia was 8.33% in the observation group, significantly lower compared with 21.67% in the control group (χ2=4.125, P=0.003).

Conclusion: Compared with the epidural anesthesia, lumbar combined with epidural anesthesia significantly enhances the quality of anesthesia, accelerates the onset of anesthesia, shortens the time of motor blockage recovery and yields less anesthesia-induced adverse reactions when applied during caesarean section.

Author(s): Yuanyuan Lu, Qinqin Cao, Shengxing Zheng, Mingpin Hu, Jun Li
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