Biomedical Research

Objective: To evaluate the diagnostic efficacy and safety of EBUS-TBNA for biopsy for pulmonary
sarcoidosis.
Methods: Seventy eight patients with suspected sarcoidosis were retrospectively included in the present
work. The included patients were received either mediastinoscopy (n=491), EBUS-TBNA (n=14),
transbronchial biopsy (EBB) (n=102) or EBUS-TBNA+EBBs (n=3) to obtain tissue specimens for
pathological diagnosis.
Results: The positive rate of EBUS-TBNA+EBB and Mediastinoscopy was 100% which was significant
higher than that of EBUS-TBNA and EBB with statistical difference (p<0.05). The medical expenses
during the hospitalization were significantly different among the groups (p<0.05). The average
hospitalization costs for mediastinoscopy were significantly higher than those for endoscopy such as
EBUS-TBNA (p<0.005). And more than 13 punctures didn’t improve the positive rate of diagnosis, but
may increase the risk of bleeding.
Conclusion: EBUS-TBNA is a safe and accurate biopsy technique. The diagnostic positive rate is similar
to the mediastinoscopy with less postoperative complications, and medical costs.

Author(s): Hui Mai, Yongxiango Zhango, Wei Jias, Yuechuan Li
Abstract | PDF

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