Biomedical Research

Objective: To analyse the effect of early rehabilitation nursing after emergency PCI on hemodynamics, quality of life, serum inflammatory factors, lipoprotein related phospholipase A2 (Lp-PLA2), IL-6 and TNF-α in patients with AMI.

Methods: 120 cases of AMI patients treated with PCI were enrolled and divided into control group and study group according to the visiting sequence, and with 60 cases in each group. Patients in the control group received routine nursing care, while patients received early rehabilitation nursing in the study group. Postoperative hemodynamics, quality of life, levels of serum inflammatory factors, lipoprotein associated phospholipase A2 (Lp-PLA2), IL-6 and TNF-α were compared between the two groups.

Results: Before the intervention, there were no significant differences between the two groups in cardiac output, systolic blood pressure, diastolic blood pressure, pulse pressure and heart rate (p>0.05). After the intervention, cardiac output of patients in the two groups significantly increased (p<0.05) and the average pulse pressure significantly decreased (p<0.05). What’s more, the improvement degree in the study group was significantly greater than the control group (P<0.05). There were no significant changes on systolic blood pressure, diastolic blood pressure and heart rate after the intervention in each group (p>0.05). Before the intervention, there was no significant difference on the quality of life and pain scores between the two groups (P>0.05). After the intervention, quality of life scores increased significantly and pain scores decreased significantly in the two groups (P<0.05), the study group changed more obviously (P<0.05). Before the intervention, there was no significant difference in serum levels of Lp-PLA2, IL-6 and TNF-αbetween the two groups (p>0.05). After the intervention, the levels of serum Lp-PLA2, IL-6 and TNF-α were significantly lower than the control group (p<0.05).

Conclusion: Early rehabilitation nursing care after emergency PCI in patients with AMI can improve hemodynamics and the quality of life. It can also reduce serum Lp-PLA2, IL-6 and TNF- levels and has certain clinical application value.

Author(s): Jun Li, Fengling Liu, Jing Lv
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