Biomedical Research

The biocompatibility of composite resins decreases with the increase of released monomer since they are cytotoxic on pulp or living tissues. Commercialy used composites should be choosen according to their biocompatibility to not jeopardize the patient’s health. Analyze of the composite biocompatibility and determination of the monomers elution of four different composite resin materials with nano filler content is completed in the study to investigate if there is difference and the most possible healty way of usage. The amount of Bis-GMA, UDMA and TEGDMA released from four different composite resins measured on three different day using the HPLC. Four groups (n=10, diameter: 5 mm, thickness: 2 mm) of each material were prepared. Samples were placed in 75% ethanol-water. On days 1, 15 and 30, 1 mL samples were taken for measurement. A total of 120 samples’ findings were analysed statistically. Bis-GMA and UDMA were released from all the materials used in the study. There were significant differences in the total monomer release of all composite resins in terms of time (P=0.001). Tetric Evoceram is the most residual monomer-releasing composite in experiment groups. The maximum amount of monomer release for all three monomers was on the 15th day. In order to reduce concerns about toxicity, taking measures to protect the pulp for example using cavity liners and bases specially in case of having less than 0.5 mm thickness of dentin. There is a need for these results to be supported by further clinical studies.

Author(s): Ezgi Sonkaya, Seyhmus Bakir, Elif Pinar Bakir
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