Biomedical Research

Previous studies showed the association between epicardial fat thickness (EFT) and cardiovascular risk. Current study was to investigate relationship between newly diagnosed essential hypertensive (NDEH) patients with the EFT and left ventricle wall thickness. A 49 newly diagnosed hypertensive patients and 36 healthy controls according to the American Hypertension Guidelines (Joint National Committee 8) were enrolled in the study. EFT and left ventricle wall thickness were measured using 2D echocardiography. The hypertensive patient’s echocardiographic values included EFT (0.61 ± 0.15 vs. 0.38 ± 0.14 p:0.001), left ventricle septal thickness (1.3 ± 0.6 vs. 1.1 ± 0.08 p<0.001), left ventricle posterior wall thickness (1.2 ± 0.13 vs. 1.1 ± 0.05 p<0.001) were greater than normotensive patients. EFT (OR 468, 95% CI 0, 535-1, 955; p=0,001) was an independent predictor of the new diagnosis of hypertension according to the multivariate regression analysis. In this study, we provide the threshold value of echocardiographic EFT for newly diagnosed hypertensive patients.

Author(s): Hüseyin Özdil, Hüseyin Katlandur, Kerem Özbek, Ahmet Keser, Ali Osman Kalkan, Seref Ulucan, Zeynettin Kaya, Müfide Öncel, M. Siddik Ülgen
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