Biomedical Research

Objective: To investigate epidemiology of relevant risk factors in oral cancer, which provides basis for oral cancer prevention.

Methods: Epidemiological questionnaire was carried out by multiple-center large-scale sample using case-control method in 8 cities in China. Investigation content included individual basic conditions, general diseases and oral diseases history, oral health habits, smoking and passive smoking, drinking water and common drink conditions, exercises and labor conditions, family history etc. This study used SAS8.2 software to do t test and χ² test for data, logistic regression to analyse the relations between various factors and oral cancer.

Results: There were significant differences in doing exercises often, drinking milk, hypertension, oral leukoplakia, bad prosthesis, smoking history, smoking-quit history, smoking with filter cigarette holder etc. between case group and the control group (P<0.05). The longer the smoking time (OR: 3.57, 95% CI: 1.58-8.06), the heavier the smoking (OR: 4.78, 95% CI: 2.07-11.11), the higher the risk degree. Exercises (OR: 0.48, 95% CI: 0.24-0.95), drinking milk (OR: 0.48, 95% CI: 0.23-1.02) and drink water management (OR: 0.53, 95% CI: 0.26-1.10) can lower risk of oral cancer.

Conclusion: Smoking is an important factor of oral cancer. Smoking filter cigarette holder cannot lower incidence of oral cancer; exercises, drinking milk, drink water management can lower incidence of oral cancer.

Author(s): Baoling Ding
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