Biomedical Research

Objective: To evaluate the value of two-dimensional strain rate imaging (STE) in detecting the alteration of regionally left ventricular long-axis systolic function in patients with slow coronary flow (SCF).

Methods: 24 patients who were with SCF but without significant coronary artery stenosis in LAD were included in left anterior descending artery (LAD) group, and 15 patients with slow flow in right coronary artery (RCA) were included in RCA group, and 20 patients who were without significant coronary stenosis or abnormal corrected thrombolysis in myocardial infarction frame count (CTFC) were included in control group. CTFC was carried on 3 groups. Peak systolic strain rate (PSRs) were measured at basal, middle and apical segments in left ventricular walls, including the septal, lateral, inferior and anterior.

Results: CTFC of left anterior descending coronary artery blood flow (39.88 ± 7.48) was significantly higher in LAD group than control group (19.84 ± 5.91, P<0.01). CTFC of right coronary artery blood flow (23.78 ± 8.15) was significantly higher in RCA group than control group (21.55 ± 8.12, P<0.01). PSRs of anterior wall in LAD group and interior wall in RCA group were significantly lower than that in control group (P<0.01). Linear regression showed that the CTFC of left anterior descending artery was negatively correlated with the PSRs of anterior wall (r=-0.55, P<0.01), as well as the CTFC of right coronary artery and the PSRs of interior wall in RCA group (-0.86, P<0.01).

Conclusions: STE can evaluate the regional left ventricular long-axis systolic function in the patients with SCF.

Author(s): Xiuxiu Fu, Zhibin Wang, Zuoyuan Chen, Meixin Liu, Wugang Wang, Junfang Li, Yong Li
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