Biomedical Research

Nano scale materials possess unique properties that are generally not seen in their bulk counterparts. Though chemical and physical methods of nano particle synthesis is widely used, the advantage of biological synthesis have gained popularity owing to their environment affability. Green synthesis of nanoparticles has gained importance in biomedical research owing to its ease of synthesis, better stability of the nanoparticles and cost effectiveness. Cadmium sulphide nanoparticles (CdS) have been extensively studied to have potential applications in the field of biomedical research and imaging studies.In the present study, CdS nanoparticles were synthesized using Bacillus licheniformis as the precursor. The thus synthesized CdS nanoparticles were characterized by scanning electron microscopy and the nano dimension of the particle was confirmed. Four different concentrations of CdS nanoparticles were tested to assess its genotoxicity using Drosophila melanogaster as the in-vivo model. Additionally, the antimicrobial property of CdS was also examined by well diffusion and macro dilution method. The results suggested significant antimicrobial activity and lack of genotoxicity of CdS nanoparticles.

Author(s): Padmini V Sekar, V Deepa Parvathi, Sumitha R
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