Biomedical Research

Objective: To explore the patients with liver cirrhosis complicated by abdominal cavity infection IL8 and IL10 and serum calcitonin original value (PCT) in clinical examination.

Methods: From July 2016 to February 2017, collected from digestive internal medicine diagnosis of liver cirrhosis associated with Spontaneous Bacterial Peritonitis (SBP) 50 cases; Simple ascites liver cirrhosis 50 cases; 50 cases of healthy subjects, respectively for SBP group, the SBP group and healthy group. In three groups of patients with peripheral blood were separately measured related indicators, IL8 were compared, IL10, PCT levels in three groups of patients serum and IL8 IL10 in SBP group and non SBP levels in patients with ascites, the comparison.

Results: The determination of three groups of patients in the serum IL8 and IL10, PCT levels found that non SBP and SBP group in the serum IL8 and IL10, PCT levels were significantly higher than that of healthy group, P<0.05, the difference was statistically significant; SBP group in the serum IL8 IL10, PCT levels were significantly higher than that of non SBP group, P<0.05, the difference was statistically significant; The determination of the SBP and SBP group IL8 in patients with ascites, IL10 levels found; SBP group of IL8 in ascites, IL10 levels were significantly higher than that of non SBP group, P<0.05, the difference was statistically significant.

Conclusion: IL8, IL10 and serum calcitonin (PCT) in the diagnosis of hepatocirrhosis with ascites not only has important meaning, and to estimate the severity of the patients, is worth popularizing in clinical use and further study.

Author(s): Xingpeng Xiao, Yifan Jia, Rong Guo, Xuan He, Hanling Ren
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