Biomedical Research

Objective: To analyze influence of the function and the structure of right pulmonary artery hypertension patients by echocardiography.

Methods: A total of 50 patients with pulmonary hypertension accepted by our hospital from March 2013 to April 2014 were selected by random number table, and randomly selected 50 healthy people as control group for medical examination in our hospital in the same period. Echocardiography examination was implemented for all patients. Recorded and compared two groups of patients with their tricuspid regurgitation area (ATR), the inner diameter of the inferior vena cava (DIVC), right ventricular end-diastolic volume (EDV), right ventricular end-systolic volume (ESV), right ventricular ejection fraction (RV-EF), left ventricular diameter (LVTD), right ventricular diameter (RVTD), pulmonary trunk diameter (DMPA), and right pulmonary artery (DRPA), left pulmonary artery (DLPA), tricuspid annulus systolic displacement (TAPSE ), right cardiac work index (RIMP), right ventricular fractional area change (FAC), tricuspid annulus peak systolic velocity (s'), tricuspid annulus peak early diastolic velocity (e'), tricuspid annulus diastolic Late peak velocity (a'), and calculates RVTD/LVTD, e'/a', left ventricular ejection fraction (LVEF).

Results: The echocardiography showed that right ventricular structure (ATR, RVEDA, RVESA, LVTD, RVTD, DMPA, DRPA, DLPA) of pulmonary hypertension compared with the control group, their difference was statistically significant (P<0.05); pulmonary right ventricular function (TAPSE, RIMP, FAC, s', e ', a')in pulmonary hypertension patients compared with those on control group, there was significant difference (P<0.05); and RVTD/LVTD, e'/a', LVEF of pulmonary hypertension were also different from control group (P<0.05).

Conclusion: Echocardiography showed that, patients with pulmonary hypertension will lead to decline in right heart dysfunction and enlarge the right heart becomes, echocardiography has a good effect for diagnosis, treatment and prognosis of patients with pulmonary hypertension.

Author(s): Zhao Ping
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