Biomedical Research

The Aim of this Study was to see the effect of single bout of Intense Exercise on production of Pro- Oxidant molecules or Oxidative Stress promoters by measuring the Serum Malondialdehyde (MDA) in the Sports Persons. Malondialdehyde (MDA) is produced after the action of Reactive Oxygen Species (ROS) on Lipids in the membranes of the cells specially contracting Muscle cells. This Study was done on 60 Sports Persons who were playing outdoor sports like Hockey,Football,Medium distance running for last 1 year or more. Informed Written Consent was taken from the Subjects and the Institutional Ethical Committee clearance was obtained. Blood samples were taken before and after the bout of intense exercise and Serum MDA levels were estimated. Paired‘t’ test was applied for statistical evaluation of the data generated using SPSS(Statistical package for Social Studies) Version 17.0 software.The study showed statistically significant increase in the levels of Serum MDA after the bout of Intense Exercise (p value <0.05 with Confidence Interval of 95%).The Study shows increased Oxidative Stress during the Exercise in Sports Persons which there by decreases the performance of the Sports Persons by decreasing the contraction of the muscles and producing fatigue. Further Studies in future needs to be done after giving various Antioxidants like Vitamin E &C and food supplements having high Antioxidant levels to these Sports Persons and see the effect of dietary supplementation of these on the performance of the Sports Persons so that if beneficial effect is seen the performance of Sport persons could be increased.

Author(s): Mohammad Shadab, Najmul Islam, Zamirullah Khan, Fauzia Khan, Mohammad Mobarak Hossain
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