Biomedical Research

Aim: The aim of our study was to investigate the changes in renal functions as well as body mass index and lipid profiles of morbid obese patients that underwent Sleeve Gastrectomy (SG) by comparing them with patients that received Balloon Gastroplasty (BG) treatment.

Materials and method: This is a retrospective study. For preoperative and postoperative periods (between 4 and 5 months), the parameters related to patients’ fasting blood sugar and insulin, lipid profile, Body Mass Index (BMI), liver function tests and Creatinine (Cr) were recorded, and Glomerular Filtration Rate (GFR) values were calculated according to MDRD (Modification of Diet in Renal Disease Study) and CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) formulations.

Results: Groups were similar according to age, baseline creatinine, CKD-EPI and MDRD levels and BMI values. With regard to renal function, there was a significant decrease in Cr values and significant increases in CKD-EPI and MDRD levels in this group of patients (p values; 0.010, 0.022, 0.029, respectively). There was no significant difference between preoperative and postoperative Cr, CKD-EPI and MDRD values of patients that underwent balloon gastroplasty (p values; 0.421, 0.581, 0.316 respectively).

Discussion: Obesity is a risk factor for chronic kidney disease. Abnormal kidney functions are seen more commonly in morbid obese patients. SG enables weight loss, and thus contributes to the improvement of renal functions.

Author(s): Murat Çilekar, Göknur Yorulmaz, Hüseyin Balcioglu, Muzaffer Bilgin, Ugur Bilge
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