Biomedical Research

Objectives: The purpose of this review is to provide a general update on clinical studies of revascularization which is frequently pronounced in recent endodontic literature.

Materials and Methods: A PubMED search was carried out to retrieve articles pertaining to clinical attempts on revascularization. Articles extending until 2014 were retrieved. Filtering was performed to make necessary exclusions and an overall number of 62 articles were included.

Results: Though a search of the available literature shows that there are variations among different authors in terms of treatment strategies in revascularization, the methodology appears to be a reliable and predictable treatment option.

Conclusion: The establishment of a well-standardized protocol will render revascularization to be more strongly accepted as a universal treatment modality.

Clinical Relevance: Revascularization is a conservative methodology whereby proliferation of a new connective tissue into a previously infected and necrotic pulp space is expected. In case a correct strategy is followed, continuation of root development with concurrent thickening of root canal walls will provide many advantages both for the patient and the clinician. With more standardized treatment protocols awaited for the future, the methodology will be better established in routine clinical practice.

Author(s): Esra Pamukçu Güven, Meriç Karapinar-Kazandag, Jale Tanalp
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