Biomedical Research

Objective: To identify predictive factors which helps in screening the healthy Chinese pregnant women who were at high risk of developing Gestational Diabetes Mellitus (GDM).

Materials and Methods: Medical records of healthy Chinese pregnant women who had given birth to baby at department of obstetrics, University Hospital of Hubei, China in 2014-2015 were reviewed. We reviewed the records of each healthy postnatal women met WHO criteria for diagnosis of diabetes mellitus during their pregnancy (GDM case), and who were not diagnosed with GDM (control, non- GDM group), and data were analysed using univariate analysis.

Result: A total of 300 post natal women with GDM were compared with equal number of matched patients in each group was enrolled, and possible risk factor associated with GDM was assessed using validated questionnaire. Univariate analysis revealed that there was significant associated of increased body mass index, family history of GDM, history of stillbirth, miscarriages and abortion with development of GDM.

Conclusion: Increased body mass index, family history of GDM, history of stillbirth, miscarriages, abortion and psychological stress during pregnancy are key predictors of GDM among Chinese pregnant women. These prognostic factors help in screening the pregnant women who were at high risk of developing GDM. We encourage increasing awareness of risk factor of GDM, which could lead to decrease incidences of GDM among healthy pregnant women.

Author(s): Lan-Yu Liu, Yan-Ling Zhang, Li Li
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