Biomedical Research

Acute myocardial infarction is one of the important reasons of death and unhealthiness in the world. The present study was undertaken to investigate the changes in serum lipids and lipoproteins in patients with acute myocardial infarction. This study was performed in the Biochemistry and Metabolic Disorder Research Center of Gorgan, Golestan province (South East of Caspian Sea), Iran in 2011.The levels of lipid profile were significantly changed in the acute myocardial infarction patients. acute myocardial infarction patients had significantly higher levels of total cholesterol, LDL-cholesterol, VLDLcholesterol, TG, LDL-cholesterol /HDL-cholesterol, total cholesterol /HDL-cholesterol, LDH, CPK and CPK-MB and lower level of HDL-cholesterol, as compared to the control subjects. We found a significant association of lipid profiles with acute myocardial infarction. Changing of dietary and social activity habits of people in this area can help to prevent future atherogenic damaging in AMI patients. Changing of dietary and social activity habits of people in this area can help to prevent future atherogenic damaging in AMI patients. Reduced serum HDL-cholesterol in our study subjects may be one of the effective reasonable lipid disorders in AMI patients.

Author(s): Ahmad Shirafkan, Abdoljalal Marjani and Farhad Zaker
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