Biomedical Research

Introduction: Tuberculosis is one of the greatest causes of death caused by infectious diseases. Almost one third of the world population (meant 2 billion) are infected by tuberculosis and vulnerable to tuberculosis. Diabetes is one of the most common non contagious diseases in the world. This disease is the fourth or fifth cause of death in the most of developed countries. The relationship between tuberculosis and diabetes had been introduced years ago and diabetes is considered as a threatening factor in tuberculosis in the research history. Not only tuberculosis is prevalent among diabetic persons, but also diabetic can affect the appearances of imaging of tuberculosis. Material and methods: This is a kind of analytic study, a case control study, which was carried out between years 93-94 in Zabol. In this study, the radiographic findings from the patients suffering from pulmonary tuberculosis in diabetic patients and not diabetic patients are compared. These radiographies handed in to a radiologist and the radiologic findings of these graphs from the anatomic location (upper and lower half of the right and left bellows), Presence or absence of cavities, nodules, density and pleural involvement were recoded and compared with diabetic and non-diabetic group. After gathering of the data using SPSS software, descriptive statistics was presented in the form of (frequency, percent) graphs and a chi-square test (p<0/05) was used to analysing and comparing of the results of diabetic and un-diabetic patients. Result: The population of the study was consisted of Chest radiograph for 124 TB patients which 61 (49/19%) were suffering from diabetics. In this study, 45 (71/43%) non-diabetic and 42 (65/85%) diabetic patients were women (p=0/7). There were 12 (19/67%) diabetic TB patients and 3 (4/76%) nondiabetic- TB patients with the consolidation of middle part of left lung (p=0/01) and 8 (13/11%) diabetic TB and 1 (1/59%) non-diabetic TB with reticulonoduler infiltration of lower part of left lung (p=0/02). There was no significant deference in rest of the radiographic results. Discussion and conclusion: The findings of this study indicate that reticulonoduler infiltration and consolidation of lower and middle part of lung in TB diabetic patients is more than TB non-diabetic patients and diabetes can affect findings of pulmonary tuberculosis radiography.

Author(s): Saeide Saeidi
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