Biomedical Research

Objective: To investigate the therapeutic effectiveness of Geng’s treatment for gastroesophageal anastomosis during gastroesophagostomy in preventing anastomotic fistula, anastomotic stenosis and gastroesophageal reflux.

Methods: 310 patients with esophagus squamous cancer were selected in our hospital from February 2016 to November 2016. Patients were divided into traditional treatment group and Geng’s treatment group according to their willing and physician’s recommendation. Patients in traditional treatment group were subjected to traditional treatment for gastroesophageal anastomosis in gastroesophagostomy after esophageal cancer resection, while Geng’s treatment for gastroesophageal anastomosis was applied in Geng’s treatment group.

Results: Among 155 patients in traditional treatment group, anastomotic fistula was observed in 5 cases (3.4%), anastomotic stenosis was observed in 6 cases (3.8%) and gastroesophageal reflux was observed in 40 cases (25.8%), while in Geng’s treatment, no anastomotic fistula was observed, anastomotic stenosis was observed in 5 cases (3.4%) and gastroesophageal reflux was observed in 2 cases (1.3%). Significant differences in the incidence rates of anastomotic fistula and gastroesophageal reflux were found between two groups (p<0.01), but no significant difference was found in incidence rate of anastomotic stenosis (p>0.05).

Conclusion: Geng's treatment method is simple, convenient and innovative. Compared with traditional treatment method, this novel method can significant reduce the incidence of anastomotic fistula and gastroesophageal reflux.

Author(s): Huang Xiaoyu, Geng Mingfei, He Xin, Zhou Fuyou, Cao Jianwei, Hu Chongming, Fu Donghong, Li Jian, Zhu Dongshan, Xu Jiangong
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