Biomedical Research

Objective: Our objective is to explore the effect of psychological status on postoperative nutrition, immune function and life quality in elderly patients with gastric cancer.

Methods: 100 elderly patients with gastric cancer between September, 2012-November, 2014 were selected, and randomly divided into observation group and control group. There were 50 cases in the control group who received routine nursing treatment, and 50 cases in the observation group who received active psychological intervention based on routine nursing. Nutrition status, immune function and life quality in two groups before and after treatment were compared.

Results: Nutrition status, immune function and life quality were not different between the observation group and the control group before treatment (P>0.05); the body mass, body fat content and prealbumin in the observation group after treatment were not different from the control group (P>0.05); after treatment, the body protein content and albumin content in the observation group were higher than the control group, which were different (P<0.05); the number of CD3+, CD4+ and CD8+ cells in the observational group were significantly higher than the control group, which were different (P<0.05), the ratio of CD4+/CD8+ in the observation group was higher than the control group, however there was no significant difference (P>0.05); the QLQ-C30 questionnaire was used to evaluate the life quality, and the results showed that the social function of patients in the observation group after treatment was not different from the control group (P>0.05), however, the scores of physical function, cognitive function and emotional function were better than the control group, which were different (P<0.05).

Conclusion: The nutritional status, immune function and life quality can be significantly improved in elderly gastric cancer patients with positive psychological status, which is worthy of clinical promotion.

Author(s): Xiaoling Qin, Chaoxia Jing, Rongxin Zheng, Lixiaoyuan Xu, Ting Wu, Yuan Ma, Yao Guo, Wenwen Liu
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