Biomedical Research

The severe coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally. By now no specific drug has been proven effective for the treatment of patients with COVID-19. RenQingMangJue (RQMJ), as a traditional Tibetan medicine (TTM) for detoxification, was shown beneficial for digestive diseases and biological toxicity. In this study, RQMJ capsule (RQMJ-C) was used to treat COVID-19 positive patients combined with conventional treatments. Patients with RQMJ-C taken orally once in a day for 10 days showed improvement in main symptoms like fever, weakness and cough, compared to the control patients. Moreover, RQMJ-C associated with a difference in time to clinical improvement in fever, weakness, cough, pharyngodynia, chest distress and digestive symptoms for example poor appetite. RQMJ-C was proven safe and no side-effect within 10 days’ treatment. Therefore, RQMJ-C could be beneficial for the treatment of COVID-19 symptoms but that needs further investigation in a larger population and a longer term.

Author(s): Yu Wang, Guozhen Ma, Xudong Tian, Yibing Zhang, Xia Song, Zhiming Zhang
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