Biomedical Research

Necrotizing fasciitis may be caused by a variety of organism . The progression of the disease may be gradual or have a fulminant course. We report a case of septicaemia, gangrene and fulminant necrotizing fasciitis caused by Vibrio Vulnificus with fatal outcome. The patient expired inspite of I.V antibiotics and amputation of the affected limb. Transmission to men is through contact with skin, mucosa or wounds exposed to sea water, and/or consumption of certain undercooked fish or raw shell , specially during the summer months. Significant risk factors for fulminant course of the disease include preexisting liver disease and im-munocompromised states. This infection should be clinically suspected and recognized from its typical history of exposure to sea water and fulminant clinical progress as a delay in di-agnosis and treatment may result in considerable mortality.

Author(s): Hazem M Zakaria
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