Biomedical Research

Coralline biomaterials for repair of brain damage

Joint Event on 2^nd International Conference on Tissue Science and Molecular Biology, Stem Cells & Separation Techniques
June 06-07, 2019 | London, UK

Danny Baranes

Ariel University, Israel

Scientific Tracks Abstracts : Biomed Res

Abstract:

Biomaterials can provide supportive microenvironment for cell growth and exciting opportunities for tissue regeneration. We found that biomaterials derived from the calcium carbonate skeleton of corals in the crystalline form of aragonite are protective and nurturing scaffolds for nervous tissue growth and survival in vitro. Moreover, implantation of coral skeleton into brain wounds generated following traumatic brain injury in mice causes tissue restoration and functional recovery. Implanted mice showed elevated level of glial fibrillary acidic protein and nestin, markers of nervous tissue generation, as well as reduced anxiety, elevated learning capacity and improved recovery from motor impairment, compared to injured but not implanted mice. These results place coralline scaffolds as a potential new mean to repair damage in the central nervous system.

Biography:

Danny Baranes has established his experience in neuroscience in the lab of the Nobel laureate Dr. Eric Kandel at Columbia University, New York, in the field of learning and memory. He was the first to use coral skeletons scaffolds for brain tissue engineering. He publishes his research in leading international scientific journals and conferences. He is an associate professor and head of the department of molecular biology at Ariel University, Israel. 

E-mail: dannyb@ariel.com

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