Biomedical Research

SYNTHESIS, PROPERTIES AND APPLICATIONS OF NOBLE METAL NANOPARTICLE-BIOMOLECULE INTEGRATION

Joint Event on Global Congress on BIOTECHNOLOGY & Annual Congress on EMERGING MATERIALS AND NANOTECHNOLOGY
September 06-07 , 2018 | Bangkok , Thailand

Xianfang Zhu

Xiamen University, China

Posters & Accepted Abstracts : Biomed Res

DOI: 10.4066/biomedicalresearch-C4-011

Abstract:

Noble metal nanoparticles, such as gold or silver nanoparticles and nanorods exhibit unique photonic and electronic properties. Functionalization of noble metal nanoparticles with biomolecules (e.g., protein and DNA) has numerous applications in catalysis, delivery, therapy, imaging, sensing, constructing nanostructure and controlling structure of biomolecules. In this paper, we review recent research about noble metal nanoparticle-biomolecule integration from the following three aspects: synthesis of noble metal nanoparticle-biomolecule integration, including electrostatic adsorption, direct chemisorption of thiol derivation, covalent binding through bifunctional linkers and specific affinity interaction; photonic properties and bioactivation of the nobel metal nanoparticle-biomolecule conjugation; applications in biosensor, imaging, diagnosis and therapy in medicine, and assembly of nanoparticle. The special attention has been paid on the conjugation of noble metal nanoparticle and biomolecule as well as the most recent related applications.

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