Biomedical Research

Objective: To investigate the reason of autogenous arteriovenous fistula failure by analyzing the clinical data of 32 hemodialysis patients in the Department of Nephrology in recent years.

Methods: A total of 32 end-stage renal disease patients who had forearm arteriovenous fistula failure in our hospital from February 2010 to February 2012 were selected, and another 66 patients who had the successful forearm arteriovenous fistula surgery in the same hospital during the same period were selected. The preoperative morning fasting blood hemoglobin (Hb), cholesterol (CHOL), fibrinogen (Fib), parathyroid hormone (PTH), blood glucose and preoperative blood pressure were collected for statistical analysis.

Results: The cephalic vein and radial artery diameter of the experimental group were significantly less than those of the control group (p<0.05). The cephalic vein and the radial artery diameters were the main risk factors of fistula failure, the smaller the diameter, the greater the risk of failure (p<0.05). The PTH level in the experimental group were significantly higher than that in the control group (p<0.05). Logistic regression analysis considered that PTH was the risk factor of arteriovenous fistula failure (p<0.05). Logistic regression analysis showed that the preoperative systolic blood pressure and diastolic blood pressure of two groups were related with the success of arteriovenous fistula surgery, the lower the blood pressure, the easily the arteriovenous fistula failure (p<0.05).

Conclusions: The main reason of autogenous arteriovenous fistula failure is the cephalic vein and the radial artery diameters, the smaller the diameter,

Author(s): Jie Sheng, Rong-kuan Li
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